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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f0118c20b3b5ce1c65a1dcb21adf694929274ccd444c6f40d6e2087583b7cd4' 
  AND token = 'avAU4iV+6o7B72FjKKD3PkL636MTMFAwd5VX0TvA7RA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}