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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e49f0dd8bac2e794e0d896d3175165953eba444cb5c585088034b5e6a731d7d1' 
  AND token = 'hVUNE0SMG75uHsVbsCgAW2snJZVF4RRyyGajT/xXMI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}