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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41d40a5618c1aa99485082bba63f3634b5c3ba4e14c358d43b77ddecf0f30a78' 
  AND token = 'Yl8+LDp3reYoiGoB1BhVLR6dh7FfSQ3rT2zx0UeS5us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}