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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '398fa3cc0b308d0384b32b0a2391ce752807dbce573669e0a36a34feeefd6224' 
  AND token = 'DW3fY/5ZI5htENZUrbLB0CTo0ijtuF+sptQPbzaXO3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}