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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15fb9d2fb69bb1ff73b4460e0d862631aadcb530c55639e75ed6559c2ba6f219' 
  AND token = 'UJgW24+S4KPNRuyQEPfCq2nVKaw2IDXNCbVwSf2jtMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}