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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '754964fec6e416bb15211917c4690fed0f8ca427da8914c9abde4bfbef3d45bc' 
  AND token = 'Ue4nkVXukAtuaYRmUisEsTxO2YYSQGnfKxJSKVJGyS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}