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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d72f7509dc77816f21a62ae9a980aa86acb099a11c22fb1689cdf5b7c14bdb6' 
  AND token = 'xDRV32BvX987CULeq18F6juUYH3ouqWe4ijA/G2NZwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}