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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4d8b379022716f3a6be8c8fc97ccbad3bdebacfe22f0e886b64261f20f8357d' 
  AND token = '1IQ89VLGcBDkY1kUkvRyifqfDm7k+OW4wq7IAcAA1Yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}