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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f8627601dae0ae2060c2136cd40060dbdf982bc42bf6a7196d16aff9f65897d' 
  AND token = 'b6p8c45IWWXUEZue7vtU/3+3JqXSq5RYzHkXDzgJ3oE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}