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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f7110110b5d88072c4438057a10176e680c285e20cc51e40897cb9444dd207e' 
  AND token = 'CXR9ktv+7QQac1WcQAkBvkI2zNXalV9cKrk50LfGQIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}