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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '052547a4a64ab38778999ec0cd9a6f9b12e92b716b857c522b111d230cb90d2c' 
  AND token = 'dkCpkW1zE9IOuPTfEl7IUOHy6GuFyiCUu4gJKUtRNgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}