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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36011ef550cabd661326997b90c1bce12eaf973d78fc5263684a3bea17d905e0' 
  AND token = 'EO5XjCC4a87K0bmoS9gUoT7wOQXr+3L2hIOZT5CaAag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}