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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73ea814b30296a3d3da811aa769caf61347f54dad24f8e5b96c5014142baad39' 
  AND token = 'JaCGblMpnGWVj7YDx4PUHzQMiWdi28u/6RZ01+a8oUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}