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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ad146a45d36beacfed17f3636ba4c4462e5b0922fa038f8677f6a675c661ffc' 
  AND token = 'WCDOB4BdtrXCi+tDUCe/9Y5xk+L4rysxq42bsX3WM18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}