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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3049cc823fa0db661e385df9838241dcf3e68e0aa29f70b21b2808d39bc0ae0' 
  AND token = 'ja+5Lf8o+RbTwJZzDc4gypo547nHFpan6VRFRUV5/aI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}