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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e66e2151e1b7693c84f855271c6f12f4e92fe7d48e8bcc20549c81dac0002d6' 
  AND token = 'MYdRkzqH8fE7qUi7ADHPMRMIn1JBXNrxh2EmjoXDxuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}