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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf0fbf6d8e4338a60dbbe51cf1032461f0e6f650792c29fe7ab571496b3e1995' 
  AND token = 'muyFNjGPSDHuc8zfEQ4NaHRAODRGTBnNEmS2ssEhe/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}