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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b440e851243e3522a81aefc3bb642d514e4ae713f50ec1d230d4cfab586c306' 
  AND token = 'U3vjrm+5e7FBmbe4f3DWx/j9AVR9IAUNHJpnYqU0TOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}