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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9250fd928926da693c9952620bf1d52667f1a3f9e7ba4788f5f4f8e05e03e3fb' 
  AND token = 'tmc61XftBJv7zfx26Y3FI/kvkbm4A2kbf5ORudYbSMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}