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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb77acdbf6cf71331add6beac9dd9cc444723539184f795bf8a0559a5e9d0c74' 
  AND token = 'oeAAX+4lGR6tf9hR++d+0S2o2PedxypfP7/Lp2Hfhi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}