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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8de5d907f977a266f5a21578c61de23b785b7bf427873b3ec48813f21b29267e' 
  AND token = 'JDgDO39JV2Pc0paYvIjNX/D2KKydR9HfRyvUn4IAK2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}