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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '092c5ce0605906223c9d6d8bb3d169d033e0d3d7d2fd6627211718a154fb0075' 
  AND token = 'uR3c/Vo/9hMrp3InRFxG8JkQG3XE0hY1zWt3/c1pKxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}