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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bd8ac7dbca015499a2e54014b9f2fac869f3684a64572f2ef7eaa2ac06afb49' 
  AND token = '6dYJpO0eBj8ZP3O6enUqpnGkXdokwQDP2Wu3Fl63XTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}