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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '151da1f15c7c099b679ddab33df20d7df2dca4a167a7f2b138b312282322ce49' 
  AND token = '1Nr5ZAQgcKaowXZEnGaUHRbb9YE1muIl21nFbZ0qPEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}