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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b371144cad732962bbb8d4c050a0cbd9de28702a47b48c9e4d4b3396949ee18' 
  AND token = 'W73pWduR1ia13DxPOMtlkRMvs4NVtX4dhL+HPSIkIXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}