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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60ec3dca03398e0be5682aaf4449db5d6c85369e3e3ca33971256a369994c1fe' 
  AND token = 'YSCTUvZEx/T3C2IZce1HHNGQZwBPDd4QF7iy+Luu+s4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}