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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22bdeff51e093c8710bf27a5cb2ddce05a532cd7b68eacd99508dc0452eff63f' 
  AND token = 'LACaTXtA1ItZi3fhp/MXqEQu1BCs8PjDhHzEX/7aKtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}