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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '367d39fa44016937ea0cc7ed0dec521d3be741e95a42954df55719418ce558b6' 
  AND token = 'P1cJtlXgK/drLIMgdxJ19fFzGF05n7ifCmHDAv/Fst4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}