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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb72ef9c3b38519b3fe33e871c6b4fd3bece28c03f1c15014eeaf07f48d435a1' 
  AND token = 'mYQpwe8Q6ekkIg17zr94Dp7N2EA1vQS/kvQWrxKYqp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}