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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21ec1db2fb6a548e065223481c2b9d46d227706231c29868b891ee2bcef048cb' 
  AND token = 'nb4HxqS9BqLUILSeHbzb9Nz36y+e9OyfnAXFZUmqpUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}