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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e100a1d0978b6548ed2c2752925b9d6d19878f5bf35cab93021a51abb8ad29e' 
  AND token = 'JTXHwFVCfRU6kzH/sRnX6rNnmOHSAZueH9LjK3AQizc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}