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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '341d54b431774ae31e733c9a4c311a98ce410fb9303a0c20bb71cea85a106195' 
  AND token = 'aDzNnPLl5Oa/l6BbM9ea6lx7SzGjoOEmWhb+RpD7l6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}