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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81cd1fe5acb17eea7a04788e39a4bde39fd1d84e0a3f9b080c80e5a431932d89' 
  AND token = 'e3eF4R2kfaHx+kV1OexyvACoFCKFjpAwXv8kR0RWOrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}