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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a3327d2c55675fdd69b0595c5622cc4b849878a21402a78815c9539a98b2d9c' 
  AND token = 'GDYohRA85MfjHdUkeswTkoGuR7L2sEsa5jBjtUttjx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}