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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f950632d4989f10dfcaea9c624c72d9e3f8a0a418312598248229e2285f35bc' 
  AND token = 'VrDgMTkPzHBPql0NRe2UgQGaSrbwioDilN8VVeF1S84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}