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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f951c144227fe70f2b5f9ac0e426189bd1007a759b5c620e28199e8f4090bc6d' 
  AND token = 'AnRlyDrMMxRHIS5R+BFG0z4uklpo9xuMJBM0JGhdqRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}