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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6193a8e4570a4a8da5612ee4efe256cfb3df1ce2e46f2ce7b7178b3250f655ba' 
  AND token = 'UM6UM1M73Ahk+aH6YZfhlYN/Wez1CvO2YgJqgvL115c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}