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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b3f74e56692cb8747704aae248c44481b8b779dd77d954f5e05998f255c354e' 
  AND token = 'FjmfquOveL4fcAY9+2u7Bx7ltmuP9uDhK0lskEqSFFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}