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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9365439a824ba2474255629c607e372c95a31e0626a4e82b7463fda807b65ffa' 
  AND token = '07kQXbNQIUJ3lDIcMjqSMATh7dt5UyaSEOcIT8MnTHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}