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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9775823737083dc48ef992df5bf49fe7a76e645878a4267892f52983af7b7bc8' 
  AND token = 'ePwn9ry0zLK26XXntpCIIl7XHgWzT3kgYR5z+P4F9Fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}