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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ef7e4433ade858012c3309e0413b7456552fec3254d4401896b9d38103fff0f' 
  AND token = '1Z7VncQA2oBEA+1vBnOSFsdXAnIFsL6I6CiadxCSCXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}