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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2515fc4a05e5ee4932a5b065197a8442e7c4c291e18928b0b0b80dcdfd36ca8d' 
  AND token = 'Ks4ShP3NZR8VoKWKNU770dE+XNvYq8SEQqmrr84D7jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}