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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f2521b2ef357207189a442487b6acd28418a1d9586723a97c211d54bf52595f' 
  AND token = 'G5oEiK2BMxRHIlk9CVoYGEHLgnQWI+sG72rrHo9xtPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}