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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3648fd357e33bcd7476e8e33a54d7541d61a2f3f558f8e046a1529763c8a6139' 
  AND token = 'Cqu9sLNKSMqpWYL6wVMgIT8yvEM1y1TT2f6E10iEP8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}