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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ce454de95227dc4d8d3da13b40b498fa86f91d3465a169f19c20fceceed1c08' 
  AND token = 'iovUzP6vkJG/ggKaOv4LyjzagfFUi+sV4iCynEYdukk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}