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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29f06ca6003e6c6d740fb68c20c2f28c4236d3a34e1d2a2b534b037052721895' 
  AND token = 'fvQknBdbifiVKkW9wrfM9sP8neokbxEwhh8qcR8g2To=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}