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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9143741d6f414bf2c8f76db51250bc200d827ee4efaced5aabefc53df95d87d' 
  AND token = 'u054W2GT80/BdQQrIf7UZSeHie5GQVfVmT8dOEIEnsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}