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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97e325cdb157abcf025d5b9e1afa65a4f9cb29e11405e8a21a5228b1e5ff6b55' 
  AND token = 'RBu49EY2hnISw3DcduEBMlBRm/cd3twTQ1BY34UB5wY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}