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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bdc53647a838f3b9f3bfa71549c56ab1490bc0f5dbe45154dbb1774ed899c008' 
  AND token = '2jWRFpXZMEYZOY1UsW3CE4dEG81pRdNQto3Lv3ESnTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}