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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7828aefd96806c1dda1a95801a4c908538174e8491f48248fd9b808a47bca77' 
  AND token = 'U2p1ThJevRRHWmCa36zArmJ9++tfTIZQA9k9BJccFoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}